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CGMP-BINDING, CGMP-SPECIFIC 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE
Descriptors Found:
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DeCS
Descriptor
English
:
Cyclic Nucleotide Phosphodiesterases, Type 5
Descriptor
Spanish
:
Fosfodiesterasas de Nucleótidos Cíclicos Tipo 5
Descriptor
Portuguese
:
Nucleotídeo Cíclico Fosfodiesterase do Tipo 5
Synonyms
English
:
PDE5 Phosphodiesterases
Phosphodiesterase 5
Phosphodiesterase 5A
Phosphodiesterase 5A, cGMP-Specific
Phosphodiesterase Type 5
Phosphodiesterase Type V
Phosphodiesterase V
Phosphodiesterase-5
cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase
Phosphodiesterase 5A, cGMP Specific
Phosphodiesterases, PDE5
Type 5, Phosphodiesterase
Type V, Phosphodiesterase
cGMP-Specific Phosphodiesterase 5A
Tree Number:
D08.811.277.352.640.150.500
D08.811.277.352.640.155.500
D12.644.360.008.500
D12.644.360.009.500
D12.776.476.008.500
D12.776.476.009.500
Definition
English
:
A cyclic nucleotide phosphodiesterase subfamily that is highly specific for
CYCLIC GMP
. It is found predominantly in vascular
tissue
and plays an important role in regulating VASCULAR SMOOTH
MUSCLE contraction.
Entry Combination - descr/qualif
English
:
Cyclic Nucleotide Phosphodiesterases, Type 5
/
antagonists & inhibitors
use
Phosphodiesterase 5 Inhibitors
History Note
English
:
2008(1998)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52680
Unique Identifier:
D054706
Occurrence in VHL
:
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